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High GGT Level In Your Performance Horse And Significance

Updated: Mar 20, 2023

Increases in serum GGT activity are primarily indicative of cholestatic liver disease but may result from colonic displacement or the administration of drugs.

Rule of thumb:

1) When GGT, SGOT and CPK are all elevated then rule out extrahepatic cholestasis and intra-hepatic cholestasis

2) When GGT is high and SGOT and CPK are normal then rule out colonic displacement and drug induced drugs such as dexamethasone, prednisone, rifampin, and benzimidazoles.

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