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Decoding GGT in Performance Horses: Liver Support Supplements to Restore Normal Levels

Performance horses, whether involved in racing, show jumping, or other competitive disciplines, require optimal health and function to excel in their respective fields. Monitoring various blood parameters is an essential part of maintaining the overall well-being of these equine athletes. One such parameter is Gamma-Glutamyl Transferase (GGT), an enzyme found predominantly in the liver. Elevated levels of GGT in a horse's bloodwork can indicate liver dysfunction or injury. In this blog post, we will delve into the significance of GGT in performance horses and explore liver support supplements that can help restore GGT levels to normal.

Understanding GGT and Its Role

GGT is an enzyme present in various tissues throughout the body, with the highest concentrations found in the liver. It plays a crucial role in the metabolism of glutathione, a vital antioxidant responsible for neutralizing free radicals and detoxifying harmful substances in the body. Elevated levels of GGT in a horse's bloodwork can serve as an indicator of liver damage, as it leaks into the bloodstream when liver cells are injured or compromised. Interpreting Elevated GGT Levels

When GGT levels exceed the normal range in performance horses, it is essential to investigate the underlying cause. Several factors can contribute to increased GGT, including:

  1. Liver Dysfunction: Liver diseases such as hepatitis, cholangitis, or cirrhosis can cause liver cell damage and subsequently elevate GGT levels.

  2. Medications: Certain medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs) or corticosteroids, can impact liver function and increase GGT levels.

  3. Dietary Factors: Nutritional imbalances, including excessive carbohydrate intake or diets lacking essential nutrients, may affect liver health and contribute to elevated GGT.

  4. Exercise-Induced Stress: Intense exercise and training can temporarily elevate GGT levels due to the physiological stress placed on the liver.

  5. Other Causes: Infections, toxins, and certain metabolic disorders can also lead to increased GGT levels.

Liver Support Supplements for Restoring GGT Levels

To address elevated GGT levels and support liver health, several supplements can be considered:

  1. Milk Thistle (Silybum marianum): Milk thistle is a widely recognized herb known for its hepatoprotective properties. Its active ingredient, silymarin, has antioxidant and anti-inflammatory effects, helping to support liver function and promote the regeneration of liver cells.

  2. Artichoke (Cynara scolymus): Artichoke contains compounds that stimulate bile production and enhance liver detoxification processes. This herb can assist in restoring normal liver function and reducing GGT levels.

  3. N-Acetylcysteine (NAC): NAC is a precursor to glutathione, the antioxidant that GGT helps metabolize. Supplementing with NAC can boost glutathione levels, aiding in liver detoxification and reducing oxidative stress.

  4. Vitamin E: As a potent antioxidant, vitamin E helps protect liver cells from oxidative damage. Supplementing with vitamin E can support liver health and contribute to lowering GGT levels.

  5. Omega-3 Fatty Acids: Found in fish oil or flaxseed oil, omega-3 fatty acids possess anti-inflammatory properties and can help reduce liver inflammation. They also support overall cardiovascular health in horses.

It's important to note that while these supplements may be beneficial in certain cases, they should be used under the guidance of a veterinarian. Liver health is a complex matter, and a comprehensive approach considering the horse's overall well-being, diet, and exercise regimen is crucial for optimal results.


Monitoring liver health is vital for maintaining the performance and well-being of horses involved in competitive disciplines. Elevated GGT levels can indicate liver dysfunction or injury, requiring further investigation and appropriate intervention. Liver support supplements, such as milk thistle, artichoke, NAC, vitamin E, and omega-3 fatty acids, can aid in restoring normal GGT levels by supporting liver function and promoting detoxification processes. Consulting with a veterinarian is essential to develop a tailored approach based on the horse's individual needs. By prioritizing liver health, horse owners and trainers can help ensure the long-term success and vitality of their performance horses.

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