Flunixin Meglumine for Horses: Uses, Dosage, Side Effects & Safety Tips

Flunixin Meglumine is one of the most widely used non-steroidal anti-inflammatory drugs (NSAIDs) in equine medicine. Whether you're managing a performance horse, a senior equine with arthritis, or a horse recovering from colic, understanding how this powerful medication works is essential for responsible and effective care.

In this blog, we’ll explore everything horse owners need to know about Flunixin Meglumine, including its uses, dosage guidelines, potential side effects, and safety precautions.

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What Is Flunixin Meglumine?

Flunixin Meglumine (often sold under the brand names Banamine®, Flunixiject, or Prevail) is a potent NSAID used to reduce inflammation, pain, and fever in horses. It works by inhibiting the production of prostaglandins, which are chemicals that cause inflammation and pain in the body.

It is FDA-approved for use in horses and is commonly administered for a variety of conditions that cause discomfort or systemic inflammation.

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Common Uses of Flunixin Meglumine in Horses

Flunixin Meglumine is used in both emergency and long-term treatment situations. Common applications include:

1. Colic Pain Relief

Colic is one of the most frequent emergencies in equine medicine. Flunixin is often the first-line drug to manage colic-related abdominal pain and inflammation.

2. Musculoskeletal Pain and Lameness

From laminitis to arthritis or soft tissue injuries, Flunixin Meglumine helps reduce inflammation and pain, allowing horses to remain mobile and more comfortable during recovery.

3. Fever Reduction

Flunixin can help lower fevers associated with respiratory infections like strangles or shipping fever.

4. Post-Surgical Pain

After procedures such as castration or dental work, Flunixin provides effective pain control and minimizes post-operative inflammation.

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Flunixin Meglumine Dosage for Horses

💉 Typical Dosage:

1.1 mg/kg (0.5 mg/lb) of body weight once daily

Administered intravenously (IV) or orally (paste or granules)

For an average 1,000 lb horse, this translates to about 500 mg per dose.

> ⚠️ Always follow your veterinarian’s guidance. Overuse or incorrect dosing can cause serious health complications.

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How Fast Does It Work?

IV Flunixin: Acts within 15-30 minutes

Oral Paste or Granules: Takes effect in 1-2 hours

Duration of Action: Up to 12 hours

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Side Effects of Flunixin Meglumine in Horses

While Flunixin is generally safe when used as directed, prolonged or excessive use can lead to side effects:

Common Side Effects:

Gastrointestinal ulcers

Kidney damage

Dehydration-related complications

Colitis (intestinal inflammation)

Signs of Adverse Reactions:

Lethargy

Loss of appetite

Diarrhea

Dark or reduced urine output

> If you notice any of these signs, discontinue use and contact your veterinarian immediately.

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Safety Guidelines for Horse Owners

To ensure safe and effective use of Flunixin Meglumine:

✅ Use only under veterinary supervision

✅ Do not exceed 5 consecutive days of use unless prescribed

✅ Ensure the horse is well-hydrated

✅ Avoid combining with other NSAIDs (e.g., phenylbutazone)

✅ Store in a cool, dry place and use before the expiration date

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Is Flunixin Meglumine Legal for Competition Horses?

Flunixin is permitted under strict withdrawal times by many equestrian organizations, including the USEF and FEI.

USEF Withdrawal Guidelines: At least 12 hours before competition

FEI Rules: Considered a controlled medication, requiring stricter adherence and clearance periods

> Always consult your sport’s governing body and veterinarian before administering Flunixin near an event.

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Flunixin Meglumine: FAQs

❓ Can I give Flunixin orally to my horse?

Yes, Flunixin is available in oral paste and granule form. Always follow the exact dosage prescribed by your vet.

❓ Can I use Banamine in place of Bute?

While both are NSAIDs, Banamine (Flunixin) and Phenylbutazone (Bute) have different indications. Banamine is generally preferred for visceral pain (e.g., colic), while Bute is often used for lameness or joint pain.

❓ Is Flunixin safe for pregnant mares?

Use only under close veterinary supervision in pregnant mares, as NSAIDs can pose risks during certain stages of pregnancy.

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Final Thoughts

Flunixin Meglumine is an essential tool in equine veterinary care, providing fast, effective relief from pain, inflammation, and fever. However, it’s not without risk. Proper usage under veterinary supervision ensures your horse benefits from its therapeutic effects while minimizing potential side effects.

If your horse is in pain, uncomfortable from colic, or recovering from surgery, talk to your vet to see if Flunixin Meglumine is the right choice.

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Need help managing your horse’s pain?

Consult with your equine veterinarian or equine pharmacy to learn more about Flunixin Meglumine and other pain relief options.

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