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Griseofulvin for Horses: Uses, Dosage, Side Effects & Safety Guide

What is Griseofulvin?


Griseofulvin is an oral antifungal medication commonly used in horses to treat dermatophytosis, more commonly known as ringworm. It works by inhibiting fungal cell division, effectively stopping the spread of infection in the horse's skin and hair.


This antifungal is especially important in performance horses and those in communal stables where fungal infections can spread rapidly.



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Common Uses of Griseofulvin in Horses


Griseofulvin is mainly prescribed for:


Ringworm (dermatophytosis) caused by Trichophyton or Microsporum species


Fungal skin infections that do not respond to topical treatments


Preventative care during outbreaks in barns or training facilities



Ringworm is highly contagious among horses and can also spread to humans (zoonotic), making early treatment critical.



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How Griseofulvin Works in Horses


Griseofulvin binds to keratin in the skin and hair, making them resistant to fungal invasion. As new skin and hair grow, they remain free of fungal infection, helping the horse naturally shed the infected layers.



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Griseofulvin Dosage for Horses


Dosage varies based on the horse’s weight and severity of infection. It is always recommended to consult a veterinarian before administering.


Typical dosage:


5 to 10 mg per pound (10–20 mg/kg) of body weight


Administered orally once daily


Treatment duration: 2 to 6 weeks, depending on the infection severity



Griseofulvin is best given with food to enhance absorption.



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Administration Tips


Mix the crushed tablet or powder form with grain or a palatable feed.


Ensure the horse consumes the entire dose.


Monitor for any signs of gastrointestinal upset.




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Side Effects of Griseofulvin in Horses


While generally safe, Griseofulvin can cause side effects in some horses:


Common side effects:


Loss of appetite


Mild diarrhea


Lethargy



Rare but serious effects:


Liver toxicity (especially with long-term use)


Photosensitivity (increased risk of sunburn in light-colored horses)


Bone marrow suppression (extremely rare)



Note: Pregnant mares should not be given Griseofulvin, as it can cause birth defects.



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Precautions and Safety


Do not use in pregnant or breeding mares.


Avoid use in foals under 1 year unless specifically advised by a vet.


Use gloves when handling the medication to avoid exposure.


Store in a cool, dry place, away from direct sunlight.




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Griseofulvin Alternatives for Horses


In some cases, topical treatments or alternative systemic antifungals may be more suitable, such as:


Ketoconazole


Itraconazole


Topical miconazole or chlorhexidine shampoos



Always consult your veterinarian to choose the most effective treatment for your horse’s specific condition.



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Where to Buy Griseofulvin for Horses


Griseofulvin requires a prescription from a licensed veterinarian. It is available through:


Veterinary clinics


Online veterinary pharmacies


Equine medical supply stores



Make sure you’re purchasing from a reputable source to ensure quality and safety.



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Final Thoughts


Griseofulvin remains a trusted and effective antifungal treatment for ringworm in horses when used correctly. Early diagnosis and consistent treatment are key to preventing the spread of infection and maintaining equine health.


Always consult your equine veterinarian before starting treatment, and follow all dosage and safety guidelines.



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FAQs About Griseofulvin in Horses


Q: Can Griseofulvin be used for all horses?

A: It is not recommended for pregnant mares or very young foals without veterinary oversight.


Q: How long does Griseofulvin take to work in horses?

A: Visible improvement is usually seen within 1–2 weeks, but treatment should continue for the full prescribed duration.


Q: Is ringworm in horses contagious to humans?

A: Yes, it is zoonotic. Always wear gloves and practice hygiene when treating infected horses.


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