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Improve Your Horse's Performance With Acetylcysteine (NAC)

For equestrians looking to peak their horse's athletic performance, acetylcysteine (NAC) is gaining popularity as a safe and effective supplement. Acetylcysteine is a powerful antioxidant that can help reduce oxidative stress during intense exercise, leading to increased endurance and faster recovery times. In this blog post, we’ll explore the benefits of using acetylcysteine for performance horses and provide dosage recommendations.

What is Acetylcysteine?

Acetylcysteine, also known as NAC, is a modified form of the amino acid cysteine. It helps boost levels of glutathione, one of the body's main antioxidants. Antioxidants combat oxidative stress, which occurs during strenuous exercise when free radicals are produced faster than the body can neutralize them. This imbalance damages cells and contributes to fatigue. By replenishing glutathione stores, NAC enhances the horse's natural antioxidant defenses.

Benefits of Acetylcysteine for Performance Horses

There are several key ways acetylcysteine can improve athletic performance in horses:

  • Increases aerobic capacity and endurance - By reducing oxidative stress, NAC allows horses to utilize more of their aerobic capacity and train longer before fatigue sets in.

  • Accelerates recovery between workouts - The antioxidant properties of NAC help horses bounce back quicker after strenuous exercise by minimizing muscle damage.

  • Improves respiratory health - Acetylcysteine helps thin mucus secretions, opening up airways for maximum oxygen delivery during exercise.

  • Protects muscle tissue - Oxidative stress can harm muscle fibers. NAC shields tissues from free radical damage.

  • Supports immune function - Intense training depresses the immune system. NAC counteracts this effect, reducing sickness downtime.

Recommended Acetylcysteine Dosage for Horses

Most studies on acetylcysteine for horses use a dosage of 20-30 mg/kg bodyweight per day

This is further broken down:

  • 10-15 mg/kg twice daily is effective for antioxidant support.

  • Higher doses of 25-30 mg/kg twice daily are typically used during competitions or rigorous training when oxidative stress will be highest.

Always consult your veterinarian before starting supplementation to determine the appropriate NAC dosage for your horse's individual needs. Provide plenty of clean water and scale dosage up or down based on response.


Acetylcysteine is an inexpensive and safe way to gain a competitive edge. The antioxidant and anti-inflammatory properties of NAC make it an attractive option for supporting respiratory health, aiding muscle recovery, and increasing stamina in equine athletes. By reducing oxidative stress and damage from free radicals, acetylcysteine helps horses reach their performance potential.

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