Ketoconazole Powder for Horses: Uses, Benefits, and Safety

What is Ketoconazole Powder?

Ketoconazole powder is an antifungal medication commonly used in veterinary medicine, particularly for treating fungal infections in horses. As a member of the azole antifungal family, ketoconazole works by disrupting the formation of fungal cell membranes, making it highly effective against a range of dermatological and systemic fungal infections.

Why is Ketoconazole Used in Horses?

Horses are prone to a variety of fungal skin infections due to their exposure to moist environments, sweat accumulation, and prolonged contact with tack. Ketoconazole is often prescribed by equine veterinarians to treat conditions such as:

Ringworm (dermatophytosis)

Yeast infections

Malassezia dermatitis

Fungal infections of the hooves and skin folds

Key Benefits of Ketoconazole for Horses

Broad-spectrum antifungal: Effective against many fungal organisms affecting equine skin and coat.

Topical and oral options: Powder form can be compounded for easier dosing or added to feed under veterinary guidance.

Fast-acting: Often shows visible improvement in skin condition within a few days of treatment.

Reduces itch and irritation: Helps soothe inflamed, itchy skin caused by fungal overgrowth.

How to Use Ketoconazole Powder in Horses

Ketoconazole for horses is typically administered orally or topically, depending on the severity and location of the infection. In powder form, it's often mixed with feed or dissolved into a suspension.

> Note: Always consult a licensed equine veterinarian before administering ketoconazole or any other antifungal treatments to horses.

Typical Dosage (Under Veterinary Supervision)

Oral ketoconazole: 5–10 mg/kg twice daily

Duration: Often 7–14 days for topical infections, longer for systemic infections

Safety, Side Effects, and Warnings

While ketoconazole is generally safe when used correctly, it may cause side effects in some horses. Be aware of the following:

Gastrointestinal upset (loss of appetite, diarrhea)

Liver enzyme elevation (in rare cases—monitor liver function during extended use)

Avoid in pregnant or lactating mares unless advised by a vet

Use with caution when combined with other medications (it can affect liver enzyme activity and drug metabolism)

Storage and Handling of Ketoconazole Powder

Store in a cool, dry place, away from direct sunlight

Keep container tightly sealed

Use gloves or wash hands after handling to avoid skin irritation

Where to Buy Ketoconazole Powder for Horses

Ketoconazole powder is often available through veterinary compounding pharmacies or prescription equine supply stores. Make sure to:

Purchase only from reputable veterinary sources

Ensure it is formulated specifically for equine use

Never use human-formulated medications on horses without veterinary guidance

Final Thoughts

Ketoconazole powder is a proven antifungal solution for treating a variety of equine skin conditions. With proper usage and veterinary oversight, it can greatly improve your horse’s comfort and skin health.

For long-term prevention, ensure your horse has clean, dry bedding, and regularly inspect their coat and hooves—especially during humid months.

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