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Pentosan Polysulfate: Other Benefits Discovered That Horse Owners Should Know About

Updated: May 18, 2023


Pentosan polysulfate (PPS) is a medication that has become increasingly popular in the equine industry as a treatment for performance horses. PPS is a synthetic compound that is similar to heparin and has been used for many years in human medicine to treat blood clotting disorders. In recent years, it has also been found to have beneficial effects for horses. PPS works by binding to certain proteins in the body, including those found in the cartilage and synovial fluid of the joints. By doing so, PPS can help to protect and repair the cartilage, as well as reduce inflammation in the joints. This makes it an attractive option for horses that are involved in high-performance activities, such as racing or jumping, where joint stress and injury are common.

One of the key benefits of PPS is its ability to help prevent or slow the progression of osteoarthritis in horses. Osteoarthritis is a degenerative joint disease that is caused by the breakdown of cartilage in the joints. It is a common problem in older horses and those that are involved in high-impact activities. By helping to protect and repair the cartilage in the joints, PPS can help to prevent or slow the progression of osteoarthritis, which can help to extend the horse's career and improve its overall quality of life.

In addition to its effects on the joints, PPS has also been found to have other benefits for performance horses. It can help to improve circulation, which can increase the delivery of oxygen and nutrients to the muscles. This can help to improve muscle function and reduce the risk of muscle injury. PPS has also been found to have anti-inflammatory properties, which can help to reduce the risk of other types of injuries, such as tendon or ligament injuries.

PPS is typically administered as a series of injections, with the frequency and dosage depending on the individual horse and their specific needs. It is generally well-tolerated by horses, with few side effects reported. However, as with any medication, it is important to work closely with a veterinarian to ensure that the horse is receiving the appropriate dosage and to monitor for any potential adverse reactions.

Overall, PPS has become a popular option for performance horses due to its ability to help protect and repair joints, improve circulation, and reduce the risk of injury. While it is not a cure-all for all types of joint problems, it can be an effective tool for managing and preventing joint problems in horses that are involved in high-performance activities. If you are considering PPS for your horse, it is important to work closely with a veterinarian to determine the appropriate dosage and to monitor the horse for any potential side effects.


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