Ulcer Paste for Horses: A Powerful Combination of Omeprazole and Misoprostol

Equine gastric ulcers are a common but often overlooked issue in performance and sport horses. Whether you're a competitive rider or a devoted horse owner, keeping your horse's digestive system healthy is essential for optimal performance and well-being. Fortunately, a new generation of ulcer paste for horses combining omeprazole and misoprostol is showing promising results in both prevention and treatment.

Understanding Equine Gastric Ulcers

Equine Gastric Ulcer Syndrome (EGUS) affects over 60% of performance horses. Caused by excess stomach acid and stress, it can lead to:

Poor appetite

Weight loss

Behavioral changes

Poor performance

Colic symptoms

While traditional ulcer treatments like omeprazole paste (a proton pump inhibitor) have been the gold standard, adding misoprostol, a synthetic prostaglandin, introduces a dual-action formula that addresses more complex gastrointestinal issues.

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What is Omeprazole?

Omeprazole is a proton pump inhibitor (PPI) that reduces the production of gastric acid in the horse’s stomach. By lowering acidity, it allows ulcers to heal naturally and prevents new ones from forming.

Benefits of Omeprazole for Horses:

Proven efficacy in treating gastric ulcers

Ideal for performance and travel-related stress ulcers

Easy administration via oral paste

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What is Misoprostol?

Misoprostol is a prostaglandin analog that protects the stomach lining by increasing mucus and bicarbonate secretion. It also improves blood flow to the gastrointestinal tract.

Why Add Misoprostol?

While omeprazole reduces acid, misoprostol enhances the stomach's natural defenses. This is particularly useful for horses:

On long-term NSAID therapy (like phenylbutazone)

With colonic ulcers or right dorsal colitis

Who are prone to chronic digestive inflammation

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Omeprazole and Misoprostol: A Synergistic Solution

Combining omeprazole and misoprostol in one ulcer paste creates a powerful treatment for both gastric and colonic ulcers. This combination supports healing from multiple angles:

Omeprazole reduces harmful stomach acid

Misoprostol protects and heals the mucosal lining

This makes it ideal for horses with:

Severe or recurring ulcers

Multiple GI tract issues

Poor response to omeprazole alone

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How to Use Ulcer Paste Containing Omeprazole and Misoprostol

Always consult your veterinarian before starting treatment. Typical usage includes:

Dosage: Based on horse weight and ulcer severity

Duration: Often 7–28 days, followed by tapering

Administration: Oral paste, ideally before feeding

Caution:

Misoprostol is not safe for pregnant mares (can cause uterine contractions)

Use gloves when handling

Store paste according to manufacturer instructions

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Where to Buy Ulcer Paste with Omeprazole and Misoprostol

This combination may be available through veterinary compounding pharmacies or prescription-only outlets. Make sure you're sourcing it from a reputable provider and that it’s formulated for equine use.

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Final Thoughts

Gastric and colonic ulcers can seriously impact your horse’s health, mood, and performance. If your horse suffers from recurrent ulcers or shows signs of discomfort even after standard treatments, a combination ulcer paste containing omeprazole and misoprostol might be the solution.

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