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Understanding Low White Blood Cell Count and High GGT in Horses Showing Poor Coordination: Signs of EPM and Treatment with Toltrazuril
- firstchoiceequine
- 1 day ago
- 4 min read
When a horse shows poor coordination along with blood test results revealing a low white blood cell count and elevated gamma-glutamyl transferase (GGT) levels, it raises important concerns. These signs can point to a serious neurological condition called Equine Protozoal Myeloencephalitis (EPM). Recognizing these symptoms early and understanding the right treatment options can make a significant difference in your horse’s recovery.
In this post, I will explain what these blood results mean, how they relate to EPM, and why toltrazuril is an effective treatment. I will also share how trusted products from First Choice Equine can support your horse’s health during this challenging time.
What Does a Low White Blood Cell Count and High GGT Mean in Horses?
White blood cells (WBCs) are crucial for fighting infections. A low white blood cell count, known as leukopenia, suggests the horse’s immune system is weakened or under stress. This can happen due to infections, toxins, or other health issues.
Gamma-glutamyl transferase (GGT) is an enzyme found mainly in the liver. High GGT levels often indicate liver stress or damage. In horses, elevated GGT can also be linked to certain infections or inflammation affecting the liver or bile ducts.
When these two blood markers appear together—low WBC and high GGT—it signals that the horse’s body is fighting a serious problem. If the horse also shows neurological signs like poor coordination, it points toward a condition affecting the nervous system.
Recognizing Poor Coordination as a Sign of EPM
Poor coordination in horses can show as stumbling, difficulty walking straight, or weakness on one side of the body. These symptoms suggest the nervous system is not working properly.
Equine Protozoal Myeloencephalitis (EPM) is a disease caused by a protozoal parasite called Sarcocystis neurona or sometimes Neospora hughesi. The parasite infects the central nervous system, causing inflammation and damage to the brain and spinal cord.
EPM is one of the most common causes of neurological problems in horses in the United States and other parts of the world. The disease can progress quickly or slowly, and symptoms vary widely. Poor coordination is often one of the first signs horse owners notice.
How Blood Tests Help Diagnose EPM
Diagnosing EPM can be tricky because its symptoms overlap with other neurological diseases. Blood tests are an important tool to support diagnosis.
Low white blood cell count indicates the immune system is compromised or overwhelmed.
High GGT levels suggest liver involvement or systemic inflammation.
When combined with neurological signs like poor coordination, these blood results raise suspicion of EPM.
Veterinarians often use additional tests such as cerebrospinal fluid analysis and specific antibody tests to confirm EPM. However, blood work is a useful first step to identify horses that need further evaluation.
Treating EPM with Toltrazuril
Once EPM is suspected or confirmed, treatment should start promptly. Toltrazuril is a medication that targets the protozoal parasites causing EPM. It works by interfering with the parasite’s ability to reproduce and survive.
Toltrazuril has become a preferred treatment option because it is effective and generally well-tolerated by horses. It can reduce parasite load and help the horse’s nervous system recover.
Treatment usually lasts several weeks, and improvement may take time. Early intervention improves the chances of a good outcome.
Supporting Your Horse’s Recovery with First Choice Equine Products
During and after EPM treatment, supporting your horse’s overall health is vital. Products from First Choice Equine offer high-quality supplements and care items designed to promote equine wellness.
For example, their range includes:
Equine immune support supplements that help strengthen the horse’s natural defenses during recovery.
Liver support products to help manage elevated GGT levels and support liver function.
Joint and neurological health supplements that can aid in improving coordination and mobility.
Using trusted products alongside veterinary treatment can help your horse regain strength and improve quality of life.
Monitoring and Managing EPM Long Term
EPM can be a chronic condition for some horses. Even after treatment with toltrazuril, ongoing care is important.
Regular veterinary check-ups to monitor neurological function.
Blood tests to track white blood cell counts and liver enzymes.
Adjusting supplements and diet to support immune and liver health.
Providing a safe environment to prevent injuries from poor coordination.
Owners should watch for any return of symptoms and consult their vet promptly if concerns arise.
When to Contact Your Veterinarian
If your horse shows signs of poor coordination, stumbling, or weakness, especially if blood tests reveal low white blood cells and high GGT, contact your veterinarian immediately. Early diagnosis and treatment of EPM can prevent permanent damage.
Your vet may recommend blood work, neurological exams, and starting treatment with toltrazuril. They can also advise on supportive care and products to help your horse recover.
Taking care of a horse with EPM requires attention, patience, and the right tools. Understanding the meaning behind blood results like low white blood cell count and high GGT helps you act quickly. Toltrazuril offers an effective treatment option to fight the parasite causing EPM.
Combining veterinary care with quality products from First Choice Equine supports your horse’s journey back to health. Remember, early action and ongoing support make all the difference in managing this challenging condition.
If you suspect your horse may have EPM, don’t wait. Reach out to your vet and explore trusted resources to give your horse the best chance at recovery.
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